Fibromyalgia is a chronic condition that affects the musculoskeletal system and is characterized by widespread pain, stiffness, and tenderness in the muscles, tendons, and joints. It is more common in women than men and often develops in people between 30 and 50. Fibromyalgia is often accompanied by other symptoms such as fatigue, sleep problems, and cognitive difficulties. The exact cause of fibromyalgia is unknown, but it is believed to be related to a combination of factors, including genetics, infections, physical or emotional trauma, and certain medical conditions. There is no cure for fibromyalgia, but treatment can help to manage the symptoms and improve the person’s quality of life.
Fibromyalgia symptoms can vary from person to person, but the most common symptoms include widespread pain and tenderness, fatigue, sleep problems, cognitive difficulties (sometimes referred to as “fibro fog”), and stiffness. Some people with fibromyalgia may also experience headaches, irritable bowel syndrome (IBS), anxiety, and depression. Fibromyalgia symptoms can be difficult to manage and may interfere with a person’s ability to carry out daily activities, work, and enjoy life.
Fibromyalgia consists of psychological and physiological aspects. Long-term pain can bring about depression. Multiple infusions may be needed in more severe cases with mental health complications.
Those with chronic pain show an overactivity of the NMDA receptors activated by glutamate. As a non-competitive NMDA antagonist, ketamine prevents glutamate from activating the NMDA receptor.
The inhibition of the NMDA receptor may cause a build-up of free glutamate, which then activates the AMPA receptors. When surplus glutamate activates the AMPA receptor, it releases a brain-derived neurotrophic factor (BDNF). BDNF, in interaction with the mammalian target of rapamycin (mTOR), promotes new neural growth. This new growth may reroute the brain from hyperactive areas associated with chronic pain, thereby providing long-term relief.
Over the past 20 years, ketamine has demonstrated high treatment efficacy for mental health and chronic pain conditions. Initially an effective sedative on the battlefield with a wide safety margin, ketamine has become an invaluable treatment for various physical and mental issues, known for its transformative power and speedy results.
Ketamine interacts with multiple aspects of our psychology and physiology. Traditional methods like talk therapy and antidepressants can take months to start working. Ketamine therapy offers patients rapid relief, with some responding to treatments within a few hours of their first infusion session.
Researchers have discovered that ketamine provides long-term remission of pain, or at least long-term and sustained relief, even in patients resistant to other forms of fibromyalgia treatment. In studies, ketamine has been shown to reduce pain and improve the overall function of people with fibromyalgia. However, further research is needed to determine the long-term effects and safety of using ketamine to treat fibromyalgia.
How much ketamine you receive is based on your body weight. Clinicians administer ketamine at a controlled, slow pace. There are no respiratory, hallucinogenic, or cardiovascular effects during or after your infusion.
Elevate Infusion Therapy is focused on bringing our patients the latest evidence-based treatment options to help improve both physical and mental health. If you or a loved one suffers from fibromyalgia, it’s time to find relief. Elevate infusion therapy is here to help. Contact us today!